Opportunity Expired
Children’s Medical Research Institute (CMRI) was Australia’s first dedicated pediatric research facility and is now one of the nation’s most highly regarded independent medical research centers. CMRI’s research programs are supported by state-of-the-art facilities and committed research and support staff. In a collaborative effort with the University of Sydney and the Sydney Children’s Hospital Network (SCHN), CMRI has built a world-leading gene therapy program, capturing the entire translational journey from idea to therapeutic reality, including clinical viral vector manufacturing facility. Aligned with our efforts in the gene therapy space, CMRI has established the Australian first Vector and Genome Engineering Facility (VGEF) dedicated to the distribution of viral vectors and gene therapy tools and reagents. In addition to highly dedicated and motivated researchers, our achievements are made possible by a loyal network of community supporters, highly engaged donors, and the very successful Jeans for Genes® fundraising campaign.
Applications are invited for the position of Research Assistant (RA) in the Vector and Genome Engineering Facility (VGEF). Up to two positions are currently available. The successful applicant/s will be involved in the production and use of recombinant and replication-competent viral vectors, such as but not limited to, adeno-associated viral vectors (AAV), lentiviral vectors (LVV), and adenoviral vectors (Ad), as well as in maintenance and manipulation of a wide range of mammalian cell types (immortalized and pluripotent) under BSL2/2+ conditions. The successful candidate/s will also be responsible for performing basic molecular biology and QA/QC assays, including but not limited to plasmid and genomic DNA purification, molecular cloning, and PCR. In addition, the position involves undertaking routine tasks related to the maintenance of the laboratory and the preparation of standard operating procedures (SOPs). This appointment is initially for a fixed term of 12 months and continuing tenure is subject to satisfactory performance and the availability of funding
The successful candidate/s must hold a Bachelor of Science degree or equivalent and have 2+ years of experience in general molecular biology and mammalian tissue culture techniques. The candidate/s must demonstrate strong interpersonal skills and attention to detail, as well as the ability/will to improve their professional knowledge (e.g. learning new protocols and techniques). Preference will be given to applicants with prior hands-on experience working with viral vectors and mammalian cell cultures. Demonstrated knowledge and experience with both PC and MAC operating systems and proficiency with Microsoft Office, especially Excel, is required. Applications are encouraged by enthusiastic and motivated individuals with excellent technical ability and communication skills.
The successful candidate/s will be provided with a competitive remuneration package in accordance with qualifications and experience. Additional benefits include the provision of a Public Benevolent Institution salary packaging scheme and participation in an employer contributes superannuation fund.